Anti-PKM2 Antibody
Boster Bio Anti-PKM2 Antibody catalog # A01173-1. Tested in WB, IHC, IF, IP, RIP applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Pyruvate kinase PKM;2.7.1.40; Cytosolic thyroid hormone-binding protein; CTHBP; Opa-interacting protein 3; OIP-3; Pyruvate kinase 2/3; Pyruvate kinase muscle isozyme; Thyroid hormone-binding protein 1; THBP1; Tumor M2-PK; p58; PKM; OIP3, PK2, PK3, PKM2;
Gene Name
PKM
UniProt
P14618
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant full length Human PKM2.
Clonality
Polyclonal
Tissue Specificity
Specifically expressed in proliferating cells, such as embryonic stem cells, embryonic carcinoma cells, as well as cancer cells.
Applications
WB, IHC, IF, IP, RIP
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio between the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival.
Molecular Weight
57937 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Pyruvate kinase PKM
Subcellular Location
Cytoplasm
Protein Name
Pyruvate kinase PKM
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