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Anti-PBR TSPO Antibody

Boster Bio Anti-PBR TSPO Antibody catalog # A01153-1. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Translocator protein; Mitochondrial benzodiazepine receptor; PKBS; Peripheral-type benzodiazepine receptor; PBR; TSPO; BZRP, MBR;

Gene Name

TSPO

UniProt

P30536

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 124-169 of Human PBR.

Clonality

Polyclonal

Tissue Specificity

Found in many tissue types. Expressed at the highest levels under normal conditions in tissues that synthesize steroids.

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Dilution

WB: 1:500-1:2000

Form

Liquid

Function

Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme (By similarity) . Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism (PubMed:24814875), but its precise physiological role is controversial. It is apparently not required for steroid hormone biosynthesis. Was initially identified as peripheral-type benzodiazepine receptor; can also bind isoquinoline carboxamides (PubMed:1847678) .

Molecular Weight

18828 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

Translocator protein

Subcellular Location

Mitochondrion membrane

Protein Name

Translocator protein

Frequently Asked Questions

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