Anti-NOS1 (phospho-S1417) Antibody
Boster Bio Anti-NOS1 (phospho-S1417) Antibody catalog # A01070S1417. Tested in WB applications. This antibody reacts with Human.
Product Specifications
Synonyms
Nitric oxide synthase, brain;1.14.13.39; Constitutive NOS; NC-NOS; N
Gene Name
NOS1
UniProt
P29475
Host
Rabbit
Reactivity
Human
Immunogen
Synthetic phosphopeptide derived from human NOS1 around the phosphorylation site of Serine 1417
Clonality
Polyclonal
Tissue Specificity
Isoform 1 is ubiquitously expressed: detected in skeletal muscle and brain, also in testis, lung and kidney, and at low levels in heart, adrenal gland and retina. Not detected in the platelets. Isoform 3 is expressed only in testis. Isoform 4 is detected in testis, skeletal muscle, lung, and kidney, at low levels in the brain, but not in the heart and adrenal gland.
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution
WB: 1:500-1:1000
Form
Liquid
Function
Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR.
Molecular Weight
160970 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Nitric oxide synthase, brain
Subcellular Location
Cell membrane, sarcolemma; Peripheral membrane protein. Cell projection, dendritic spine . In skeletal muscle, it is localized beneath the sarcolemma of fast-twitch muscle fiber by associating with the dystrophin glycoprotein complex. In neurons, enriched in dendritic spines (By similarity) . .
Protein Name
Nitric oxide synthase, brain
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