Anti-4E-BP1 (phospho-T36) EIF4EBP1 Antibody
Boster Bio Anti-4E-BP1 (phospho-T36) EIF4EBP1 Antibody catalog # A00968T36. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Eukaryotic translation initiation factor 4E-binding protein 1;4E-BP1; eIF4E-binding protein 1; Phosphorylated heat- and acid-stable protein regulated by insulin 1; PHAS-I; EIF4EBP1;
Gene Name
EIF4EBP1
UniProt
Q13541
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic phosphorylated peptide around T37 & T46 of human eIF4EBP1 (NP_004086.1) .
Clonality
Polyclonal
Applications
WB, IHC
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
Repressor of translation initiation that regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. In contrast, hyperphosphorylated form dissociates from EIF4E, allowing interaction between EIF4G1/EIF4G3 and EIF4E, leading to initiation of translation. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways.
Molecular Weight
12580 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.bosterbio.com/datasheet?sku=A00968T36
Product MSDS
https://www.bosterbio.com/msds?sku=A00968T36
Other Gene Names
Eukaryotic translation initiation factor 4E-binding protein 1
Protein Name
Eukaryotic translation initiation factor 4E-binding protein 1
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
