Anti-p130 Cas (phospho-Y249) BCAR1 Antibody
Selected Variant
A00960Y249-1
Size: 100 µL
Boster Bio Anti-p130 Cas (phospho-Y249) BCAR1 Antibody catalog # A00960Y249-1. Tested in WB, IHC, ICC applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Breast cancer anti-estrogen resistance protein 1; CRK-associated substrate; Cas scaffolding protein family member 1; p130cas; BCAR1; CAS, CASS1, CRKAS;
Gene Name
BCAR1
UniProt
P56945
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic phosphopeptide derived from human p130 Cas around the phosphorylation site of Tyrosine 249.
Clonality
Polyclonal
Tissue Specificity
Widely expressed with an abundant expression in the testis. Low level of expression seen in the liver, thymus, and peripheral blood leukocytes. The protein has been detected in a B-cell line.
Applications
WB, IHC, ICC
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
Docking protein which plays a central coordinating role for tyrosine kinase-based signaling related to cell adhesion. Implicated in induction of cell migration. Overexpression confers antiestrogen resistance on breast cancer cells.
Molecular Weight
93372 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Breast cancer anti-estrogen resistance protein 1
Subcellular Location
Cell junction, focal adhesion
Protein Name
Breast cancer anti-estrogen resistance protein 1
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