Anti-ATF3 (N159) Antibody

Boster Bio Anti-ATF3 (N159) Antibody catalog # A00904-1. Tested in WB, IHC applications. This antibody reacts with Human, Rat.

Product Specifications

Synonyms

Cyclic AMP-dependent transcription factor ATF-3; cAMP-dependent transcription factor ATF-3; Activating transcription factor 3; ATF3;

Gene Name

ATF3

UniProt

P18847

Host

Rabbit

Reactivity

Human, Rat

Immunogen

Synthetic peptide, corresponding to Human ATF3.

Clonality

Polyclonal

Applications

WB, IHC

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Form

Liquid

Function

This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter. Isoform 2 activates transcription presumably by sequestering inhibitory cofactors away from the promoters.