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Anti-ATF2 (Phospho-T71) LRP1 Antibody

Boster Bio Anti-ATF2 (Phospho-T71) LRP1 Antibody catalog # A00829T71. Tested in WB, ICC/IF, IP applications. This antibody reacts with Human.

Product Specifications

Synonyms

Prolow-density lipoprotein receptor-related protein 1; LRP-1; Alpha-2-macroglobulin receptor

Gene Name

LRP1

UniProt

Q07954

Host

Rabbit

Reactivity

Human

Immunogen

Synthetic phospho-peptide corresponding to residues surrounding Thr71 of human ATF2

Clonality

Polyclonal

Tissue Specificity

Most abundant in liver, brain and lung.

Applications

WB, ICC, IF, IP

Purification

ProA affinity purified

Form

Liquid

Function

Endocytic receptor involved in endocytosis and in phagocytosis of apoptotic cells. Required for early embryonic development. Involved in cellular lipid homeostasis. Involved in the plasma clearance of chylomicron remnants and activated LRPAP1 (alpha 2-macroglobulin), as well as the local metabolism of complexes between plasminogen activators and their endogenous inhibitors. May modulate cellular events, such as APP metabolism, kinase-dependent intracellular signaling, neuronal calcium signaling as well as neurotransmission (PubMed:11907044, PubMed:12888553, PubMed:12713657) . Acts as an alpha-2- macroglobulin receptor (PubMed:26142438) .

Molecular Weight

504606 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

Prolow-density lipoprotein receptor-related protein 1

Subcellular Location

Low-density lipoprotein receptor-related protein 1 85 kDa subunit: Cell membrane; Single-pass type I membrane protein. Membrane, coated pit.

Protein Name

Prolow-density lipoprotein receptor-related protein 1

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