Anti-ATG12 (S129) Antibody
Boster Bio Anti-ATG12 (S129) Antibody catalog # A00820S129. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Ubiquitin-like protein ATG12; Autophagy-related protein 12; APG12-like; ATG12; APG12, APG12L;
Gene Name
ATG12
UniProt
O94817
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to residues in Human ATG12.
Clonality
Polyclonal
Tissue Specificity
Ubiquitous.
Applications
WB, IHC
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
Ubiquitin-like protein involved in autophagy vesicles formation. Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes.
Molecular Weight
15113 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Ubiquitin-like protein ATG12
Subcellular Location
Cytoplasm . Preautophagosomal structure membrane
Protein Name
Ubiquitin-like protein ATG12
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