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Anti-ACE2 (K465) Antibody

Boster Bio Anti-ACE2 (K465) Antibody catalog # A00756-1. Tested in IHC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Angiotensin-converting enzyme 2;3.4.17.23; ACE-related carboxypeptidase; Angiotensin-converting enzyme homolog; ACEH; Metalloprotease MPROT15; Processed angiotensin-converting enzyme 2; ACE2; UNQ868/PRO1885;

Gene Name

ACE2

UniProt

Q9BYF1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to amino acids 430-482 of Human ACE2.

Clonality

Polyclonal

Tissue Specificity

Expressed in endothelial cells from small and large arteries, and in arterial smooth muscle cells. Expressed in lung alveolar epithelial cells, enterocytes of the small intestine, Leydig cells and Sertoli cells (at protein level) . Expressed in heart, kidney, testis, and gastrointestinal system.

Applications

IHC

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Dilution

IHC: 1:50-1:200

Form

Liquid

Function

Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin- 13 and dynorphin-13 with high efficiency. May be an important regulator of heart function.

Molecular Weight

92463 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

Angiotensin-converting enzyme 2

Subcellular Location

Processed angiotensin-converting enzyme 2: Secreted.

Protein Name

Angiotensin-converting enzyme 2

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