Anti-Ctip1 BCL11A Antibody

B-cell lymphoma/leukemia 11A; BCL-11A; B-cell CLL/lymphoma 11A; COUP-TF-interacting protein 1; Ecotropic viral integration site 9 protein homolog; EVI-9; Zinc finger protein 856; BCL11A; CTIP1, EVI9, KIAA1809, ZNF856;

Expressed at high levels in brain, spleen thymus, bone marrow and testis. Expressed in CD34-positive myeloid precursor cells, B-cells, monocytes and megakaryocytes. Expression is tightly regulated during B-cell development.

Transcription factor associated with the BAF SWI/SNF chromatin remodeling complex (By similarity) . Repressor of fetal hemoglobin (HbF) level (PubMed:26375765) . Involved in brain development (PubMed:27453576) . Functions as a myeloid and B-cell proto-oncogene. May play important roles in leukemogenesis and hematopoiesis. Essential factor in lymphopoiesis required for B- cell formation in fetal liver. May function as a modulator of the transcriptional repression activity of ARP1 (By similarity) .