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Anti-Smad1 (phospho-S187) Antibody

Boster Bio Anti-Smad1 (phospho-S187) Antibody catalog # A00728S187. Tested in WB, IHC, ICC, IP applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Mothers against decapentaplegic homolog 1; MAD homolog 1; Mothers against DPP homolog 1; JV4-1; Mad-related protein 1; SMAD family member 1; SMAD 1; Smad1; hSMAD1; Transforming growth factor-beta-signaling protein 1; BSP-1; SMAD1; BSP1, MADH1, MADR1;

Gene Name

SMAD1

UniProt

Q15797

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic phosphopeptide derived from human Smad1 around the phosphorylation site of Serine 187.

Clonality

Polyclonal

Tissue Specificity

Ubiquitous. Highest expression seen in the heart and skeletal muscle.

Applications

WB, IHC, ICC, IP

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Form

Liquid

Function

Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD) . SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP) -mediated cardiac-specific gene expression.

Molecular Weight

52260 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

Mothers against decapentaplegic homolog 1

Subcellular Location

Cytoplasm

Protein Name

Mothers against decapentaplegic homolog 1

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