Anti-PLCG1 Antibody
Boster Bio Anti-PLCG1 Antibody catalog # A00677-1. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1;3.1.4.11; PLC-148; Phosphoinositide phospholipase C-gamma-1; Phospholipase C-II; PLC-II; Phospholipase C-gamma-1; PLC-gamma-1; PLCG1; PLC1;
Gene Name
PLCG1
UniProt
P19174
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human gamma 1 (PLCG1) (NP_002651.2) .
Clonality
Polyclonal
Applications
WB
Purification
ProA affinity purified
Dilution
WB: 1:500-1:2000
Form
Liquid
Function
Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) . Plays an important role in the regulation of intracellular signaling cascades. Becomes activated in response to ligand- mediated activation of receptor-type tyrosine kinases, such as PDGFRA, PDGFRB, FGFR1, FGFR2, FGFR3 and FGFR4. Plays a role in actin reorganization and cell migration.
Molecular Weight
148532 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
Subcellular Location
Cell projection, lamellipodium. Cell projection, ruffle. Rapidly redistributed to ruffles and lamellipodia structures in response to epidermal growth factor (EGF) treatment.
Protein Name
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
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