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Anti-PLCG1 Antibody

Boster Bio Anti-PLCG1 Antibody catalog # A00677-1. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1;3.1.4.11; PLC-148; Phosphoinositide phospholipase C-gamma-1; Phospholipase C-II; PLC-II; Phospholipase C-gamma-1; PLC-gamma-1; PLCG1; PLC1;

Gene Name

PLCG1

UniProt

P19174

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide of human gamma 1 (PLCG1) (NP_002651.2) .

Clonality

Polyclonal

Applications

WB

Purification

ProA affinity purified

Dilution

WB: 1:500-1:2000

Form

Liquid

Function

Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) . Plays an important role in the regulation of intracellular signaling cascades. Becomes activated in response to ligand- mediated activation of receptor-type tyrosine kinases, such as PDGFRA, PDGFRB, FGFR1, FGFR2, FGFR3 and FGFR4. Plays a role in actin reorganization and cell migration.

Molecular Weight

148532 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

Subcellular Location

Cell projection, lamellipodium. Cell projection, ruffle. Rapidly redistributed to ruffles and lamellipodia structures in response to epidermal growth factor (EGF) treatment.

Protein Name

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

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