Anti-Major vault protein MVP Antibody
Boster Bio Anti-Major vault protein MVP Antibody catalog # A00642-2. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Major vault protein; MVP; Lung resistance-related protein; MVP; LRP;
Gene Name
MVP
UniProt
Q14764
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein
Clonality
Polyclonal
Tissue Specificity
Present in most normal tissues. Higher expression observed in epithelial cells with secretory and excretory functions, as well as in cells chronically exposed to xenobiotics, such as bronchial cells and cells lining the intestine. Overexpressed in many multidrug-resistant cancer cells.
Applications
WB, IHC
Purification
ProA affinity purified
Form
Liquid
Function
Required for normal vault structure. Vaults are multi- subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo- cytoplasmic transport. Down-regulates IFNG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases.
Molecular Weight
99327 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Major vault protein
Subcellular Location
Cytoplasm
Protein Name
Major vault protein
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