Anti-PTPN1 Antibody
Boster Bio Anti-PTPN1 Antibody catalog # A00613-2. Tested in WB, IHC, IF applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Tyrosine-protein phosphatase non-receptor type 1;3.1.3.48; Protein-tyrosine phosphatase 1B; PTP-1B; PTPN1; PTP1B;
Gene Name
PTPN1
UniProt
P18031
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant full length Human PTPN1.
Clonality
Polyclonal
Applications
WB, IHC, IF
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
Tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. Mediates dephosphorylation of EIF2AK3/PERK; inactivating the protein kinase activity of EIF2AK3/PERK. May play an important role in CKII- and p60c-src-induced signal transduction cascades. May regulate the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion. May also regulate the hepatocyte growth factor receptor signaling pathway through dephosphorylation of MET.
Molecular Weight
49967 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Tyrosine-protein phosphatase non-receptor type 1
Subcellular Location
Endoplasmic reticulum membrane
Protein Name
Tyrosine-protein phosphatase non-receptor type 1
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