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Anti-AR (phospho-S213) Antibody

Boster Bio Anti-AR (phospho-S213) Antibody catalog # A00542S213. Tested in IHC applications. This antibody reacts with Human.

Product Specifications

Synonyms

Androgen receptor; Dihydrotestosterone receptor; Nuclear receptor subfamily 3 group C member 4; AR; DHTR, NR3C4;

Gene Name

AR

UniProt

P10275

Host

Rabbit

Reactivity

Human

Immunogen

Synthetic phosphopeptide derived from human AR around the phosphorylation site of Serine 213.

Clonality

Polyclonal

Tissue Specificity

Isoform 2 is mainly expressed in heart and skeletal muscle (PubMed:15634333) . Isoform 3 is expressed by basal and stromal cells of prostate (at protein level) (PubMed:19244107) .

Applications

IHC

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Dilution

IHC: 1:50-1:200

Form

Liquid

Function

Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins. Transcription activation is down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3.

Molecular Weight

99188 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A00542S213

Product MSDS

https://www.bosterbio.com/msds?sku=A00542S213

Other Gene Names

Androgen receptor

Subcellular Location

Nucleus

Protein Name

Androgen receptor

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