Anti-AR (E646) Antibody
Boster Bio Anti-AR (E646) Antibody catalog # A00542-2. Tested in IHC applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Androgen receptor; Dihydrotestosterone receptor; Nuclear receptor subfamily 3 group C member 4; AR; DHTR, NR3C4;
Gene Name
AR
UniProt
P10275
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 611-660 of Human AR.
Clonality
Polyclonal
Tissue Specificity
Isoform 2 is mainly expressed in heart and skeletal muscle (PubMed:15634333) . Isoform 3 is expressed by basal and stromal cells of prostate (at protein level) (PubMed:19244107) .
Applications
IHC
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution
IHC: 1:50-1:200
Form
Liquid
Function
Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins. Transcription activation is down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3.
Molecular Weight
99188 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Androgen receptor
Subcellular Location
Nucleus
Protein Name
Androgen receptor
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