Anti-TRAIL (S63) TNFSF10 Antibody
Boster Bio Anti-TRAIL (S63) TNFSF10 Antibody catalog # A00466S63. Tested in IHC, IF applications. This antibody reacts with Human.
Product Specifications
Synonyms
Tumor necrosis factor ligand superfamily member 10; Apo-2 ligand; Apo-2L; TNF-related apoptosis-inducing ligand; Protein TRAIL; CD253; TNFSF10; APO2L, TRAIL;
Gene Name
TNFSF10
UniProt
P50591
Host
Rabbit
Reactivity
Human
Immunogen
Synthetic peptide, corresponding to amino acids 50-100 of Human TRAIL.
Clonality
Polyclonal
Tissue Specificity
Widespread; most predominant in spleen, lung and prostate.
Applications
IHC, IF
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG (PubMed:26457518, PubMed:10549288) . Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis.
Molecular Weight
32509 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Tumor necrosis factor ligand superfamily member 10
Subcellular Location
Cell membrane
Protein Name
Tumor necrosis factor ligand superfamily member 10
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