Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-Beta-secretase 1 BACE1 Antibody

Boster Bio Anti-Beta-secretase 1 BACE1 Antibody catalog # A00322-2. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Beta-secretase 1 ;3.4.23.46

Gene Name

BACE1

UniProt

P56817

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human BACE1 (NP_036236.1) .

Clonality

Polyclonal

Tissue Specificity

Expressed at high levels in the brain and pancreas. In the brain, expression is highest in the substantia nigra, locus coruleus and medulla oblongata.

Applications

WB, IHC, ICC, IF

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Form

Liquid

Function

Responsible for the proteolytic processing of the amyloid precursor protein (APP) . Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. Cleaves APP with much more catalytic efficiency than for the wild-type.

Molecular Weight

55764 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A00322-2

Product MSDS

https://www.bosterbio.com/msds?sku=A00322-2

Other Gene Names

Beta-secretase 1

Subcellular Location

Cell membrane

Protein Name

Beta-secretase 1

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Pro-MCH (PMCH) Antibody
abx240144 100 µg

Pro-MCH (PMCH) Antibody

Ask
View Details
MacroH2A shRNA Plasmid (h)
sc-62575-SH 20 µg

MacroH2A shRNA Plasmid (h)

Ask
View Details
Cerium(III) fluoride, 99%
GX8403-500g 500 g

Cerium(III) fluoride, 99%

Ask
View Details
anti-Cytokeratin 19
YF-PA12894 50 ug

anti-Cytokeratin 19

Ask
View Details