Anti-CXCR-3 Antibody
Boster Bio Anti-CXCR-3 Antibody catalog # A00295-1. Tested in WB, IHC applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
C-X-C chemokine receptor type 3; CXC-R3; CXCR-3; CKR-L2; G protein-coupled receptor 9; Interferon-inducible protein 10 receptor; IP-10 receptor; CD183; CXCR3; GPR9;
Gene Name
CXCR3
UniProt
P49682
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthetic peptide, corresponding to Human CXCR-3.
Clonality
Polyclonal
Tissue Specificity
Isoform 1 and isoform 2 are mainly expressed in heart, kidney, liver and skeletal muscle. Isoform 1 is also expressed in placenta. Isoform 2 is expressed in endothelial cells. Expressed in T-cells (at protein level) .
Applications
WB, IHC
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Form
Liquid
Function
Isoform 1: Receptor for the C-X-C chemokine CXCL9, CXCL10 and CXCL11 and mediates the proliferation, survival and angiogenic activity of human mesangial cells (HMC) through a heterotrimeric G-protein signaling pathway (PubMed:12782716) . Binds to CCL21. Probably promotes cell chemotaxis response.
Molecular Weight
40660 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
C-X-C chemokine receptor type 3
Subcellular Location
Isoform 1: Cell membrane
Protein Name
C-X-C chemokine receptor type 3
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