Anti-IRS-1 (phospho-S312) Antibody
Boster Bio Anti-IRS-1 (phospho-S312) Antibody catalog # A00268S312. Tested in WB applications. This antibody reacts with Human.
Product Specifications
Synonyms
Insulin receptor substrate 1; IRS-1; IRS1;
Gene Name
IRS1
UniProt
P35568
Host
Rabbit
Reactivity
Human
Immunogen
Synthetic phosphopeptide derived from human IRS-1 around the phosphorylation site of Serine 312.
Clonality
Polyclonal
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution
WB: 1:500-1:1000
Form
Liquid
Function
May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit (By similarity) .
Molecular Weight
131591 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Insulin receptor substrate 1
Protein Name
Insulin receptor substrate 1
Curated Selection
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