Anti-Histone H2A.X H2AFX Antibody
Boster Bio Anti-Histone H2A.X H2AFX Antibody catalog # A00241-3. Tested in WB, ICC/IF, IHC, IP applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Histone H2AX; H2a/x; Histone H2A.X; H2AFX; H2AX;
Gene Name
H2AFX
UniProt
P16104
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein
Clonality
Polyclonal
Applications
WB, ICC, IF, IHC, IP
Purification
ProA affinity purified
Form
Liquid
Function
Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C- terminal phosphorylation.
Molecular Weight
15145 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.bosterbio.com/datasheet?sku=A00241-3
Product MSDS
https://www.bosterbio.com/msds?sku=A00241-3
Other Gene Names
Histone H2AX
Subcellular Location
Nucleus
Protein Name
Histone H2AX
Curated Selection
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