What is the catalog number for Anti-FTO Antibody?

The catalog number for Anti-FTO Antibody is A00219-1.

What sizes are available for Anti-FTO Antibody?

Anti-FTO Antibody is available in the following size(s): 100 µL.

Is Anti-FTO Antibody in stock?

Anti-FTO Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-FTO Antibody?

The safety data sheet for Anti-FTO Antibody is available here: https://www.bosterbio.com/msds?sku=A00219-1.

Anti-FTO Antibody

Boster Bio Anti-FTO Antibody catalog # A00219-1. Tested in WB, ICC/IF, IHC applications. This antibody reacts with Human.

Product Specifications

Synonyms

Alpha-ketoglutarate-dependent dioxygenase FTO;1.14.11.-

Gene Name

FTO

UniProt

Q9C0B1

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant protein

Clonality

Polyclonal

Tissue Specificity

Ubiquitously expressed, with relatively high expression in adrenal glands and brain; especially in hypothalamus and pituitary.

Applications

WB, ICC, IF, IHC

Purification

ProA affinity purified

Form

Liquid

Function

Dioxygenase that repairs alkylated DNA and RNA by oxidative demethylation. Has highest activity towards single- stranded RNA containing 3-methyluracil, followed by single- stranded DNA containing 3-methylthymine. Has low demethylase activity towards single-stranded DNA containing 1-methyladenine or 3-methylcytosine (PubMed:18775698, PubMed:20376003) . Specifically demethylates N (6) -methyladenosine (m6A) RNA, the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes (PubMed:22002720, PubMed:26458103) . Has no activity towards 1- methylguanine. Has no detectable activity towards double-stranded DNA. Requires molecular oxygen, alpha-ketoglutarate and iron. Contributes to the regulation of the global metabolic rate, energy expenditure and energy homeostasis. Contributes to the regulation of body size and body fat accumulation (PubMed:18775698, PubMed:20376003) . In particular, it is involved in the regulation of thermogenesis and the control of adipocyte differentiation into brown or white fat cells (PubMed:26287746) .