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Anti-Raf-B (phospho-S445) BRAF Antibody

Boster Bio Anti-Raf-B (phospho-S445) BRAF Antibody catalog # A00075S445. Tested in WB applications. This antibody reacts with Human, Rat.

Product Specifications

Synonyms

Serine/threonine-protein kinase B-raf;2.7.11.1; Proto-oncogene B-Raf; p94; v-Raf murine sarcoma viral oncogene homolog B1; BRAF; BRAF1, RAFB1;

Gene Name

BRAF

UniProt

P15056

Host

Rabbit

Reactivity

Human, Rat

Immunogen

A synthetic phosphorylated peptide around S445 of human BRAF (NP_004324.2) .

Clonality

Polyclonal

Tissue Specificity

Brain and testis.

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Dilution

WB: 1:500-1:2000

Form

Liquid

Function

Protein kinase involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May play a role in the postsynaptic responses of hippocampal neuron. Phosphorylates MAP2K1, and thereby contributes to the MAP kinase signal transduction pathway.

Molecular Weight

84437 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

Serine/threonine-protein kinase B-raf

Subcellular Location

Nucleus . Cytoplasm. Cell membrane . Colocalizes with RGS14 and RAF1 in both the cytoplasm and membranes. .

Protein Name

Serine/threonine-protein kinase B-raf

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