Anti-CKR-5 (phospho-S349) CCR5 Antibody
Boster Bio Anti-CKR-5 (phospho-S349) CCR5 Antibody catalog # A00061S349. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
C-C chemokine receptor type 5; C-C CKR-5; CC-CKR-5; CCR-5; CCR5; CHEMR13; HIV-1 fusion coreceptor; CD195; CCR5; CMKBR5;
Gene Name
CCR5
UniProt
P51681
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic phosphopeptide derived from human CKR-5 around the phosphorylation site of Serine 349.
Clonality
Polyclonal
Tissue Specificity
Highly expressed in spleen, thymus, in the myeloid cell line THP-1, in the promyeloblastic cell line KG-1a and on CD4+ and CD8+ T-cells. Medium levels in peripheral blood leukocytes and in small intestine. Low levels in ovary and lung.
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Dilution
WB: 1:500-1:1000
Form
Liquid
Function
Receptor for a number of inflammatory CC-chemokines including CCL3/MIP-1-alpha, CCL4/MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation.
Molecular Weight
40524 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
C-C chemokine receptor type 5
Subcellular Location
Cell membrane
Protein Name
C-C chemokine receptor type 5
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