(R) -Sortilin antagonist 1
(R) -Sortilin antagonist 1 is a sortilin antagonist that blocks the sortilin mediated apoptosis pathway by interfering with the binding of sortilin to its ligand pro-neurotrophin. (R) -Sortilin antagonist 1 can be used in the study of hearing loss[1].
Product Specifications
CAS Number
[2889422-86-8]
UNSPSC
12352005
Target
Neurotensin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/r-sortilin-antagonist-1.html
Purity
97.05
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(C)(C)CC[C@H](C(O)=O)NC(C(C=N1)=CC=C1OC2=CC=CC=C2)=O
Molecular Formula
C20H24N2O4
Molecular Weight
356.42
References & Citations
[1]KJØLBY Mads Fuglsang, et al. A sortilin antagonist for use in the prevention or treatment of hearing loss.WO2022074119A1.2021-10-07
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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