(rel) -Tivantinib
(rel) -Tivantinib is a potent and highly selective inhibitor of the receptor tyrosine kinase c-MET. (rel) -Tivantinib has two novel targets, GSK3α and GSK3β, which play an important role in the cellular mechanism of non-small cell lung cancer (NSCLC) [1].
Product Specifications
CAS Number
[905853-99-8]
Product Name Alternative
(rel) -ARQ 197; (rel) - (3R,4R) -ARQ 198
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
C-Met/HGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/rel-tivantinib.html
Purity
96.45
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(NC1=O)[C@@H](C2=CN3C4=C(C=CC=C42)CCC3)[C@@H]1C5=CNC6=C5C=CC=C6
Molecular Formula
C23H19N3O2
Molecular Weight
369.42
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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