NITD-2
NITD-2, a dengue virus (DENV) polymerase inhibitor, inhibits the DENV RdRp-mediated RNA elongation. NITD-2 penetrates cell membrane poorly[1].
Product Specifications
CAS Number
1197896-79-9
UNSPSC
12352005
Target
Dengue Virus; DNA/RNA Synthesis; Flavivirus
Type
Reference compound
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/nitd-2.html
Purity
99.36
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(O)C1=CC=CC=C1NS(=O)(C2=CC=CC(C3=CN(CC4=CC=CC=C4)N=C3)=C2)=O
Molecular Formula
C23H19N3O4S
Molecular Weight
433.48
References & Citations
[1]Pornwaratt Niyomrattanakit, et al. Inhibition of dengue virus polymerase by blocking of the RNA tunnel. J Virol. 2010 Jun;84 (11) :5678-86.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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