Z-IETD-AFC
Z-IETD-AFC, a specific fluorescence substrate, can be used to determine the caspase-8 catalytic activity[1].
Product Specifications
CAS Number
[219138-02-0]
UNSPSC
12171500
Target
Fluorescent Dye
Type
Dye Reagents
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/z-ietd-afc.html
Purity
99.78
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C1OC2=C(C(C(F)(F)F)=C1)C=CC(NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(OCC3=CC=CC=C3)=O)[C@H](CC)C)=O)CCC(O)=O)=O)[C@@H](C)O)=O)CC(O)=O)=O)=C2
Molecular Formula
C37H42F3N5O13
Molecular Weight
821.75
References & Citations
[1]Boudard D, et al. Increased caspase-3 activity in refractory anemias: lack of evidence for Fas pathway implication. Leukemia. 2002;16 (11) :2343-2345.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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