Rabeprazole
Rabeprazole (LY307640) is a second-generation proton pump inhibitor (PPI) that irreversibly inactivates gastric H+/K+-ATPase. Rabeprazole induces apoptosis. Rabeprazole acts as an uridine nucleoside ribohydrolase (UNH) inhibitor with an IC50 of 0.3 μM. Rabeprazole can be used for the research of gastric ulcerations and gastroesophageal reflux[1][2][3].
Product Specifications
CAS Number
117976-89-3
Product Name Alternative
LY307640
UNSPSC
12352005
Hazard Statement
H315, H319, H320
Target
Apoptosis; Bacterial; Proton Pump
Type
Reference compound
Related Pathways
Anti-infection; Apoptosis; Membrane Transporter/Ion Channel
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Rabeprazole.html
Purity
99.14
Solubility
DMSO : 20.83 mg/mL (ultrasonic)
Smiles
O=S(C1=NC2=CC=CC=C2N1)CC3=NC=CC(OCCCOC)=C3C
Molecular Formula
C18H21N3O3S
Molecular Weight
359.44
Precautions
H315, H319, H320
References & Citations
Trichomonas Vaginalis
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Citation 01
Nat Commun. 2023 Jul 14;14 (1) :4217.|Results Chem. 2024 Oct.|Front Immunol. 2022 Jun 21;13:895869.
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