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LAIR2, Human (HEK293, His)

Leukocyte-associated immunoglobulin-like receptor 2 is expressed as a soluble receptor exhibiting high affinity for various collagen molecules to which it binds in a hydroxyproline-dependent manner. LAIR2 Protein, Human (HEK293, His) is the recombinant human-derived LAIR2 protein, expressed by HEK293 , with C-6*His labeled tag.

Product Specifications

Product Name Alternative

LAIR2 Protein, Human (HEK293, His), Human, HEK293

UNSPSC

12352202

Type

Recombinant Proteins

Assay Protocol

https://www.medchemexpress.com/cytokines/lair2-protein-human-hek-293-his.html

Smiles

QEGALPRPSISAEPGTVISPGSHVTFMCRGPVGVQTFRLEREDRAKYKDSYNVFRLGPSESEARFHIDSVSEGNAGLYRCLYYKPPGWSEHSDFLELLVKESSGGPDSPDTEPGSSAGTVPGTEASGFDAP

Molecular Formula

3904 (Gene_ID) Q6ISS4-1 (Q22-P152) (Accession)

Molecular Weight

Approximately 20 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.

References & Citations

[1]Liu J, et al. Human-specific LAIR2 contributes to the high invasiveness of human extravillous trophoblast cells. Reprod Biol. 2019 Sep;19 (3) :287-292.|[2]Olde Nordkamp MJ, et al. Inhibition of the classical and lectin pathway of the complement system by recombinant LAIR-2. J Innate Immun. 2014;6 (3) :284-92.|[3]Founds SA, et al. LAIR2-expressing extravillous trophoblasts associate with maternal spiral arterioles undergoing physiologic conversion. Placenta. 2013 Mar;34 (3) :248-55.

Shipping Conditions

Room temperature in continental US; may vary elsewhere.

Scientific Category

Recombinant Proteins

Frequently Asked Questions

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