Fmoc-Arg (Pbf) -OH

Fmoc-Arg (Pbf) -OH is an arginine derivative containing amine protecting group Fmoc. Fmoc-Arg (Pbf) -OH is a building block for the introduction of Arg into SPPS (Solid-Phase Peptide Synthesis) [1][2][3].

Product Specifications

CAS Number

[154445-77-9]

UNSPSC

12352209

Hazard Statement

H302, H315, H319, H335

Target

Amino Acid Derivatives; Drug Intermediate

Type

Peptides

Related Pathways

Others

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/fmoc-arg-pbf-oh.html

Purity

99.97

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

N=C(NS(=O)(C1=C(C)C(C)=C(OC(C)(C)C2)C2=C1C)=O)NCCC[C@@H](C(O)=O)NC(OCC3C4=C(C5=C3C=CC=C5)C=CC=C4)=O

Molecular Formula

C34H40N4O7S

Molecular Weight

648.77

Precautions

H302, H315, H319, H335

References & Citations

[1]Beatriz G, et al. Successful development of a method for the incorporation of Fmoc-Arg (Pbf) -OH in solid-phase peptide synthesis using N-butylpyrrolidinone (NBP) as solvent. Green Chemistry, 2020, 22 (10) : 3162-3169.|[2]Wojciechowski JP, et al. A Facile Method to Quantify Synthetic Peptide Concentrations on Biomaterials. ACS Appl Mater Interfaces. 2024 Sep 18;16 (37) :49880-49888.|[3]Li S, et al. Inclusion complex based on N-acetyl-L-cysteine and arginine modified hydroxypropyl-β-cyclodextrin for oral insulin delivery. Carbohydr Polym. 2021 Jan 15;252:117202.