3-Hydroxypropanoic acid-pip-hydroquinone-dihydrouracil
Product Specifications
UNSPSC Description
3-hydroxypropanoic acid-pip-hydroquinone-dihydrouracil is a conjugate of E3 ligase ligand and linker that serve as a key intermediate for the synthesis of complete PROTAC HPK1 Degrader-2 (HY-162544)[1].
Target Antigen
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/3-hydroxypropanoic-acid-pip-hydroquinone-dihydrouracil.html
Smiles
O=C(N1CCN(C2=CC=C(N3C(NC(CC3)=O)=O)C=C2)CC1)CCO
Molecular Weight
346.38
References & Citations
[1]BeiGene, Ltd. Preparation of pyrrolo[2,3-b]pyrazine-based bifunctional compounds as HPK1 degraders and the use thereof. World Intellectual Property Organization, WO2023006063 A1 2023-02-02
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-162546/3-Hydroxypropanoic-acid-pip-hydroquinone-dihydrouracil-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-162546/
Clinical Information
No Development Reported
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