3-Hydroxypropanoic acid-pip-hydroquinone-dihydrouracil
Selected Variant
HY-162546
Size: 1 Each
3-hydroxypropanoic acid-pip-hydroquinone-dihydrouracil is a conjugate of E3 ligase ligand and linker that serve as a key intermediate for the synthesis of complete PROTAC HPK1 Degrader-2.
Product Specifications
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/3-hydroxypropanoic-acid-pip-hydroquinone-dihydrouracil.html
Smiles
O=C(N1CCN(C2=CC=C(N3C(NC(CC3)=O)=O)C=C2)CC1)CCO
Molecular Formula
C17H22N4O4
Molecular Weight
346.38
References & Citations
[1]BeiGene, Ltd. Preparation of pyrrolo[2,3-b]pyrazine-based bifunctional compounds as HPK1 degraders and the use thereof. World Intellectual Property Organization, WO2023006063 A1 2023-02-02
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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