N-Nitrosoanatabine
(R, S) -N-Nitrosoanatabine (N-NAT) is a tobacco-specific nitrosamine (TSNA) that has been found in tobacco, tobacco products, and electronic cigarettes. The (S) enantiomer comprises approximately 80% of the N-NAT found in commercial and research cigarettes and smokeless tobacco.3 Unlike other TSNAs, N-NAT is not carcinogenic in rats when administered at doses of 1, 3, and 9 mmol/kg.
Product Specifications
CAS Number
887407-16-1
Product Name Alternative
N-NAT; N'-Nitrosoanatabine
UNSPSC
12352005
Hazard Statement
H301
Target
Biochemical Assay Reagents
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/n-nitrosoanatabine.html
Purity
99.70
Smiles
O=NN1CC=CCC1C2=CC=CN=C2
Molecular Formula
C10H11N3O
Molecular Weight
189.21
Precautions
H301
References & Citations
[1]Hoffmann, et al. Dose-response study of the carcinogenicity of tobacco-specific N-nitrosamines in F344 rats. J. Cancer Res. Clin. Oncol. 108 (1), 81-86 (1984) .
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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