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N-Nitrosoanatabine

(R, S) -N-Nitrosoanatabine (N-NAT) is a tobacco-specific nitrosamine (TSNA) that has been found in tobacco, tobacco products, and electronic cigarettes. The (S) enantiomer comprises approximately 80% of the N-NAT found in commercial and research cigarettes and smokeless tobacco.3 Unlike other TSNAs, N-NAT is not carcinogenic in rats when administered at doses of 1, 3, and 9 mmol/kg.

Product Specifications

CAS Number

[887407-16-1]

Product Name Alternative

N-NAT; N'-Nitrosoanatabine

UNSPSC

12352005

Hazard Statement

H301

Target

Biochemical Assay Reagents

Type

Reference compound

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/n-nitrosoanatabine.html

Purity

99.70

Smiles

O=NN1CC=CCC1C2=CC=CN=C2

Molecular Formula

C10H11N3O

Molecular Weight

189.21

Precautions

H301

References & Citations

[1]Hoffmann, et al. Dose-response study of the carcinogenicity of tobacco-specific N-nitrosamines in F344 rats. J. Cancer Res. Clin. Oncol. 108 (1), 81-86 (1984) .

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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