IMAB027
Product Specifications
UNSPSC Description
IMAB027 (ASP1650) is a specific anti-CLDN6 mAb, while CLDN6 (Claudin 6) is a tight junction membrane protein, aberrantly expressed in various human cancer types, ovarian cancers particularly. IMAB 027 shows anti-tumor activity, and induces apoptosis in CLDN6+ ovarian and testicular cancer cell lines[1].
Target Antigen
HCV
Type
Inhibitory Antibodies
Related Pathways
Anti-infection
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/imab027.html
Purity
98.98
Solubility
10 mM in DMSO
Smiles
[IMAB027]
References & Citations
[1]Türeci Ö, t al. The anti-claudin 6 antibody, IMAB027, induces antibody-dependent cellular and complement-dependent cytotoxicity in claudin 6-expressing cancer cells[J]. Cancer Research, 2018, 78(13_Supplement): 882-882.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P99413/IMAB027-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P99413/IMAB027-SDS-MedChemExpress.pdf
Clinical Information
Phase 2
CAS Number
1650599-68-0
Available Sizes
Curated Selection
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