IMAB027
IMAB027 (ASP1650) is a specific anti-CLDN6 mAb, while CLDN6 (Claudin 6) is a tight junction membrane protein, aberrantly expressed in various human cancer types, ovarian cancers particularly. IMAB 027 shows anti-tumor activity, and induces apoptosis in CLDN6+ ovarian and testicular cancer cell lines[1].
Product Specifications
CAS Number
[1650599-68-0]
Product Name Alternative
ASP1650
UNSPSC
12352203
Target
HCV
Type
Inhibitory Antibodies
Related Pathways
Anti-infection
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/imab027.html
Purity
99.89
Solubility
10 mM in DMSO
Smiles
[IMAB027]
Molecular Weight
(144.42 kDa)
References & Citations
[1]Türeci Ö, t al. The anti-claudin 6 antibody, IMAB027, induces antibody-dependent cellular and complement-dependent cytotoxicity in claudin 6-expressing cancer cells[J]. Cancer Research, 2018, 78 (13_Supplement) : 882-882.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 2
Available Sizes
Curated Selection
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