M2I-1
Product Specifications
UNSPSC Description
M2I-1 is a Mad2 inhibitor targeting the binding of Mad2 to Cdc20, an essential protein-protein interaction (PPI) within the spindle assembly checkpoint (SAC)[1].
Target Antigen
Immune Checkpoint
Type
Reference compound
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/M2I-1.html
Purity
98.0
Solubility
DMSO : ≥ 32 mg/mL
Smiles
O=C(/C(C(N1)=O)=C\C2=CC=C(N(CC(C)C)CC(C)C)C([N+]([O-])=O)=C2)NC1=S
Molecular Weight
404.48
References & Citations
[1]Johanna Kastl et al. Mad2 Inhibitor-1 (M2I-1): A Small Molecule Protein-Protein Interaction Inhibitor Targeting the Mitotic Spindle Assembly Checkpoint. ACS Chem. Biol., 2015, 10 (7), pp 1661-1666.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-100341/M2I-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-100341/M2I-1-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
312271-03-7
Available Sizes
Curated Selection
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