Human FGF-20 Protein, His tag (Animal-Free)

Fibroblast Growth Factors-20 (FGF-20) is a 23.5 kDa member of the fibroblast Growth Factors with 211 amino acid residues. FGF-20 is mainly expressed from microglial cells. FGF-20 can regulate central nervous development and function, regulate the survival of dopaminergic neurons via FGF/FGFR-dependent signaling pathway.

Product Specifications

Background

Fibroblast growth factor 20 (FGF-20) is a member of FGF gene family, which currently has 22 members. Based on its structure, it is further classified as a member of FGF-9 subfamily. FGF-20 is known to bind to heparin. There are no reports of alternative splicing forms. However, it is known that there are three kinds of amino acid polymorphisms, and the single nucleotide polymorphism in the non-coding region that may affect the expression has a strong correlation with the risk of developing Parkinson's disease

Product Name Alternative

FGFK

Accession Number

Q9NP95

Tag

FGF-20

Type

Cytokines and proteins

Applications

His tag

Purity

>98% as determined by SDS-PAGE.

Activity

Measure by its ability to induce 3T3 cells proliferation.The ED50 for this effect is 1.3-3.2 ng/mL

Molecular Weight

24.24 kDa

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Features & Benefits

Endotoxin: <0.1 EU per 1 μg of the protein by the LAL method.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Lyophilized protein product should be stored desiccated below -18°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (5% HSA , 10%FBS or 0.1%BSA) . Please prevent freeze-thaw cycles

Protein Length

The recombinant Human FGF-20 consists of 209 amino acids and predicts a molecular mass of 24.24 kDa

Formulation

Lyophilized from PBS, pH 8.0

Applications Notes

Human

Other Product Names

FGFK

Recommended Usage

Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized recombinant protein to a concentration of 0.1-1 mg/mL using the buffer we provided, and keep at room temperature for at least 20 min to fully dissolve. Please avoid vortex vigorously