Cas9-IN-3
Product Specifications
UNSPSC Description
Cas9-IN-3 is a potent Cas9 inhibitor (IC50=28 μM). CRISPR/Cas systems have revolutionized gene editing in various species[1].
Target Antigen
CRISPR/Cas9
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/cas9-in-3.html
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
O=C(N1CCC(CC1)C)C2=CC=CC(C3=CC=CC=C3)=C2
Molecular Weight
279.38
References & Citations
[1]Lee SW, et al. Identification and Optimization of Novel Small-Molecule Cas9 Inhibitors by Cell-Based High-Throughput Screening. J Med Chem. 2022;65(4):3266-3305.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-145692/Cas9-IN-3-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-145692/Cas9-IN-3-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2322051-02-3
Available Sizes
Curated Selection
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