Cas9-IN-3
Cas9-IN-3 is a potent Cas9 inhibitor (IC50=28 μM) [1].
Product Specifications
CAS Number
[2322051-02-3]
UNSPSC
12352005
Target
Bacterial; CRISPR/Cas9
Type
Reference compound
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/cas9-in-3.html
Purity
99.64
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
O=C(N1CCC(CC1)C)C2=CC=CC(C3=CC=CC=C3)=C2
Molecular Formula
C19H21NO
Molecular Weight
279.38
References & Citations
[1]Lee SW, et al. Identification and Optimization of Novel Small-Molecule Cas9 Inhibitors by Cell-Based High-Throughput Screening. J Med Chem. 2022;65 (4) :3266-3305.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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