Anethole trithione

Anethole trithione, a sulfur heterocyclic choleretic, is a bile secretion-stimulating agent. Anethole trithione enhances salivary secretion and increases mAChRs, and can be used for dry mouth research[1][2].

Product Specifications

CAS Number

[532-11-6]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

MAChR

Type

Natural Products

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Cancer-programmed cell death

Field of Research

Cancer; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Anethole-trithione.html

Purity

99.76

Solubility

DMSO : 12.5 mg/mL (ultrasonic)

Smiles

S=C1SSC(C2=CC=C(OC)C=C2)=C1

Molecular Formula

C10H8OS3

Molecular Weight

240.36

Precautions

H302, H315, H319, H335

References & Citations

[1]T Nagano, et al. Enhancement of salivary secretion and neuropeptide (substance P, alpha-calcitonin gene-related peptide) levels in saliva by chronic anethole trithione treatment. J Pharm Pharmacol. 2001 Dec;53 (12) :1697-702.|[2]Sheng Huang, et al. Synthesis, Characterization, and In Vivo Evaluation of Desmethyl Anethole Trithione Phosphate Prodrug for Ameliorating Cerebral Ischemia-Reperfusion Injury in Rats. ACS Omega. 2020 Feb 24;5 (9) :4595-4602.|[3]Y Ukai, et al. Chronic anethole trithione treatment enhances the salivary secretion and increases the muscarinic acetylcholine receptors in the rat submaxillary gland. Arch Int Pharmacodyn Ther. 1984 Oct;271 (2) :206-12.