AACA
AACA is an inhibitor for sclerostin, that binds sclerostin on loop3 region with Kd of 15.4 nM. AACA exhibits anti-osteoporosis activity through Wnt signaling pathway[1].
Product Specifications
CAS Number
[2515609-54-6]
UNSPSC
12352005
Target
Wnt
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/aaca.html
Purity
99.39
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(CNC(C1=CC=C(C=C1)C#CCNC(C)=O)=O)O
Molecular Formula
C14H14N2O4
Molecular Weight
274.27
References & Citations
[1]Yu S, et al., Discovery of the small molecular inhibitors against sclerostin loop3 as potential anti-osteoporosis agents by structural based virtual screening and molecular design. Eur J Med Chem. 2024 Apr 16;271:116414.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![Mouse Monoclonal Disialoganglioside GD3 Antibody (MB3.6) [FITC]](https://cdn.genprice.uk/genprice/uk/genprice2.webp)