Purified Anti-Human CD52 Antibody[Campath-1G]
Product Specifications
Background
CD52, also known as Cambridge pathology antigen 1 (CAMPATH-1), is a 25-29 kD glycoprotein containing a large N-linked carbohydrate moiety. The actual molecule of CD52 is only 8-9 kD. It is expressed in the male reproductive tract and on virtually all lymphocytes (T and B cells), as well as macrophages/monocytes, eosinophils, and red cells. CD52 is thought to play a role in carrying and orienting carbohydrates. CD52 is a potent target for complement-mediated lysis and antibody-mediated cellular cytotoxicity and has been used as a depletion target for chronic lymphocytic leukemia (CLL) /lymphoma and immunosuppression.
Abbreviation
CD52
Gene ID
1043
UniProt
P31358
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant Human CD52 protein
Target
CDW; Epididymal secretory protein E; Human epididymis-specific protein; CAMPATH; CAMPATH-1; CAMPATH-1 antigen; CD52 antigen; CD52 molecule; Epididymal secretory protein E5; HEL-S-171mP; Human epididymis-specific protein 5; CDW52; HE5; CD52; HE5
Clonality
Monoclonal
Clone
Campath-1G
Conjugation
Unconjugated
Applications
FCM
Field of Research
Immunology
Purification
>98%, Protein A/G purified
Concentration
≥ 1 mg/mL
Dilution
66
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
Shipping Conditions
Ice bag
Storage Conditions
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Isotype
Rabbit IgG, κ
Available Sizes
Curated Selection
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