(+) -SHIN1
(+) -SHIN1 ((+) -RZ-2994) is an active (+) enantiomer of SHIN1[1].
Product Specifications
CAS Number
2443966-90-1
Product Name Alternative
(+) -RZ-2994
UNSPSC
12352005
Target
SHMT
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/shin1-1.html
Purity
99.37
Solubility
DMSO : ≥ 100 mg/mL
Smiles
OCC1=CC(C2=CC=CC=C2)=CC([C@@]3(C(C(C)=NN4)=C4OC(N)=C3C#N)C(C)C)=C1
Molecular Formula
C24H24N4O2
Molecular Weight
400.47
References & Citations
[1]Ducker GS, et al. Human SHMT inhibitors reveal defective glycine import as a targetable metabolic vulnerability of diffuse large B-cell lymphoma. Proc Natl Acad Sci U S A. 2017 Oct 24;114 (43) :11404-11409.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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