Sporogen AO-1

Sporogen AO-1 is a fungal metabolite originally isolated from the fungusAspergillus oryzae. Sporogen AO-1 has significant antimalarial activity againstplasmodium falciparum, with an IC50 value of 1.53 μM, and also has certain cytotoxicity[1].

Product Specifications

CAS Number

[88418-12-6]

UNSPSC

12352005

Hazard Statement

H315-H319-H335

Target

Parasite

Type

Natural Products

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/sporogen-ao-1.html

Solubility

10 mM in DMSO

Smiles

CC([C@]1(C(C=C2CC[C@H]3O)=O)[C@]([C@@]2([C@H]3C)C)([H])O1)=C

Molecular Formula

C15H20O3

Molecular Weight

248.32

Precautions

P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501

References & Citations

[1]Charuwan Daengrot, et al. Eremophilane Sesquiterpenes and Diphenyl Thioethers from the Soil Fungus Penicillium copticola PSU-RSPG138. J Nat Prod. 2015 Apr 24;78 (4) :615-22.