Carbazeran
Carbazeran, a potent phosphodiesterase inhibitor, is aldehyde oxidase substrate. Carbazeran can be used for the research of metabolic disease[1].
Product Specifications
CAS Number
[70724-25-3]
UNSPSC
12352005
Hazard Statement
H301
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/carbazeran.html
Purity
99.94
Solubility
DMSO : 100 mg/mL
Smiles
COC1=CC2=C(C=C1OC)C=NN=C2N3CCC(OC(NCC)=O)CC3
Molecular Formula
C18H24N4O4
Molecular Weight
360.41
Precautions
H301
References & Citations
[1]Uehara S, et al. Human Aldehyde Oxidase 1-Mediated Carbazeran Oxidation in Chimeric TK-NOG Mice Transplanted with Human Hepatocytes. Drug Metab Dispos. 2020 Jul;48 (7) :580-586.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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