3-Fluoro-L-tyrosine

3-Fluoro-L-tyrosine is a tyrosine analogue, inhibits transamination by tyrosine aminotransferase (TAT) . And 3-FluoroL-tyrosine has been shown to be biologically incorporated into proteins in place of tyrosine. 3-Fluoro-L-tyrosine pretends to be the substrate of rat liver tyrosine aminotransferase, markedly disturbs the Tyr-TAT association[1][2].

Product Specifications

CAS Number

[7423-96-3]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Amino Acid Derivatives

Type

Reference compound

Related Pathways

Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/3-fluoro-l-tyrosine.html

Purity

99.99

Solubility

H2O : 2 mg/mL (ultrasonic)

Smiles

C1=CC(=C(C=C1C[C@@H](C(=O)O)N)F)O

Molecular Formula

C9H10FNO3

Molecular Weight

199.18

Precautions

H302, H315, H319, H335

References & Citations

[1]Iron A, et al. Action of the phosphonic analogue of tyrosine and of other tyrosine derivatives on rat liver tyrosine aminotransferase. Amino Acids. 1993 Feb;5 (1) :33-7.|[2]Phillips RS, et al. Effects of tyrosine ring fluorination on rates and equilibria of formation of intermediates in the reactions of carbon-carbon lyases. Eur J Biochem. 1997 Mar 1;244 (2) :658-63.