Nicaraven

Nicaraven is a novel chemically synthesized hydroxyl radical-specific scavenger.

Product Specifications

CAS Number

[79455-30-4]

UNSPSC

12352005

Hazard Statement

H302

Target

Others

Type

Reference compound

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/Nicaraven.html

Purity

99.96

Solubility

DMSO : ≥ 100 mg/mL|H2O : ≥ 50 mg/mL

Smiles

CC(NC(C1=CC=CN=C1)=O)CNC(C2=CC=CN=C2)=O

Molecular Formula

C15H16N4O2

Molecular Weight

284.31

Precautions

H302

References & Citations

[1]Komiya T, et al. A novel free radical scavenger, nicaraven, inhibits human platelet aggregation in vitro. Clin Neuropharmacol. 1999 Jan-Feb;22 (1) :11-4.|[2]Yokota R, et al. A novel hydroxyl radical scavenger, nicaraven, protects the liver from warm ischemia and reperfusion injury. Surgery. 2000 Jun;127 (6) :661-9.|[3]Ali H, et al. The potential benefits of nicaraven to protect against radiation-induced injury in hematopoietic stem/progenitor cells with relative low dose exposures.|[4]Nicaraven attenuates radiation-induced injury in hematopoietic stem/progenitor cells in mice. PLoS One. 2013;8 (3) :e60023.