Enpp/Carbonic anhydrase-IN-1
Product Specifications
UNSPSC Description
Enpp/Carbonic anhydrase-IN-1 (compound 1e) is a potent Enpp and carbonic anhydrase inhibitor with IC50s of 1.36, 1.35, 3.00, 0.88, 1.02 μM for NPP1, NPP2, NPP3, CA-II, CA-IX respectively. Enpp/Carbonic anhydrase-IN-1 shows antiproliferative activity for cancer cells and low cytotoxic against normal cells. Enpp/Carbonic anhydrase-IN-1 induces Apoptosis[1].
Target Antigen
Apoptosis; Carbonic Anhydrase; Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Apoptosis;Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/enpp-carbonic-anhydrase-in-1.html
Solubility
DMSO : 100 mg/mL (ultrasonic;warming;heat to 50°C)
Smiles
O=S(C1=CC=CC=C1)(OC2=CC=C(C=C2)NC(C34CC5CC(C4)CC(C3)C5)=O)=O
Molecular Weight
411.51
References & Citations
[1]Afnan I.Shahin, et al. Design and synthesis of new adamantyl derivatives as promising antiproliferative agents. European Journal of Medicinal Chemistry, 2022.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-151916/Enpp-Carbonic-anhydrase-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-151916/Enpp-Carbonic-anhydrase-IN-1-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2883495-35-8
Available Sizes
Curated Selection
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